Arrhythmogenic Right Ventricular Cardiomyopathy/ Dysplasia in Adults: A Case Report with Literature Review
Published: 2022-06-27
Page: 227-233
Issue: 2022 - Volume 5 [Issue 1]
B. E. Ovaga *
Department of Cardiology, University Hospital Center IBN Rochd, Casablanca, Morocco.
B. Mohammed Sidi
Department of Cardiology, University Hospital Center IBN Rochd, Casablanca, Morocco.
S. I. Harouna
Department of Cardiology, University Hospital Center IBN Rochd, Casablanca, Morocco.
P. M. Mulendele
Department of Cardiology, University Hospital Center IBN Rochd, Casablanca, Morocco.
M. Njie
Department of Cardiology, University Hospital Center IBN Rochd, Casablanca, Morocco.
M. Haboub
Department of Cardiology, University Hospital Center IBN Rochd, Casablanca, Morocco.
L. Azzouzi
Department of Cardiology, University Hospital Center IBN Rochd, Casablanca, Morocco.
R. Habbal
Department of Cardiology, University Hospital Center IBN Rochd, Casablanca, Morocco.
*Author to whom correspondence should be addressed.
Abstract
Arrhythmogenic right ventricular cardiomyopathy/ dysplasia (ARVC/D) is a cardiomyopathy of genetic origin, caused by abnormalities of desmosomes, characterized on the physiopathological level by a fibro-adipose infiltration replacing the myocardium of the right ventricle and the clinical level by an electrical instability leading to ventricular arrhythmias. ARVC/D peaks in frequency between the ages of 30 and 50. Diagnostic criteria have been established to retain the diagnosis of ARVC/D. Imaging, especially magnetic resonance imaging (MRI), plays a vital role in this diagnosis. We report the observation of a 48-year-old man, a former smoker, with a family history of the sudden death of a sister during a bicycle race and who has been complaining for several years of palpitations. Clinical presentation, electrical signs, cardiac ultrasound, and imaging findings lead to the diagnosis of ARVC/D. According to this observation, the authors describe the authors review the literature on this rare entity and discuss the different therapeutic approaches.
Keywords: Arrhythmogenic dysplasia of the right ventricle/ genetics, ventricular tachycardia, electrocardiogram, magnetic resonance imaging